Dimethyl p-(methylthio)phenyl phosphate

  • 4-Methylthiophenyldimethyl phosphate
  • O,O-Dimethyl o-(4-methylmercaptophenyl) phosphate
  • GC 6506
  • HA-1200
Formula
C9H13O4PS
Structure
Description
Colorless liquid.
Uses
Contact & systemic insecticide & acaricide former use.

Registry Numbers and Inventories.
CAS
3254-63-5
EC Index Number
015-119-00-3
RTECS
TC5075000
RTECS class
Agricultural Chemical and Pesticide
UN (DOT)
3018
Beilstein/Gmelin
2458575
Beilstein Reference
5-06
EPA OPP
370100

Properties.
Formula
C9H13O4PS
Formula mass
248.25
Boiling point, °C
301
Vapor pressure, mmHg
0.0019 (25 C)
Density
1.273 g/cm3 (20 C)
Solubility in water
98 mg/L (20 C)
Partition coefficient, pKow
1.67
Heat of vaporization
51.9 kJ/mol

Hazards and Protection.
Storage
Do not freeze, store in cool, dry place. Keep out of reach of children. Keep in original containers in secure location. Rooms used for storage only should be soundly constructed and fitted with secure locks. Floors should be kept clear and pesticides clearly identified if repacking is carried out in storage rooms, adequate light should be available; floors should be impervious and sound. Pesticides pesticides containers must be provided with labels indicating the degree of toxicity of the product they contain. The labels must not only give a short description of how to use the prepn, but also state basis precautions to be taken when applying it. Organophosphorus pesticides pesticides of any degree of toxicity should be transported in containers which are clearly labelled, leak-proof, and not easily damaged. They should never be transported beside, or above any type of food, and all spillages should be immediately reported.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Rubber gloves, protective clothing, goggles, respirator. Workers handling and applying organophosphate pesticides must be given personal protective equipment comprising overalls made of a tight fabric or polyvinyl chloride, gloves, and rubber boots. The eyes should be protected by goggles. Wear appropriate chemical protective gloves, boots and goggles. Wear appropriate chemical protective clothing. If contact with the material anticipated, wear appropriate chemical protective clothing.
Respirators
Respiratory protection (supplied-air respirator with full facepiece or self-contained breathing apparatus) should be available where these compounds are manufactured or used and should be worn in case of emergency and overexposure.<BR>Wear a respirator with an activated-carbon gas filter cartridge affording protection for a determined number of working hours.
Small spills/leaks
(Non-Specific -- Organophosphorus Pesticides) Keep material out of water courses and sewer. Build dikes to contain flow as necessary. Use water spray to knock down vapor. Do not touch spilled material. (Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Remove and isolate contaminated clothing at the site. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal.
Stability
Decomposes at 269-284 C, hydrolyzed by alkali (ph 9.5) At 37.5 Deg c.

Fire.
Flash Point,°C
136
Fire fighting
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Wear positive pressure breathing apparatus and special protective clothing. Dike fire control water for later disposal; do not scatter the material.(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam. Move container from fire area if you can do it without risk. Fight fire from maximum distance.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Containers may explode when heated.
Combustion products
When heated to decomp, can emit highly toxic fumes of oxides of phosphorous.

Health.
Exposure effects
Fever, low heart rate and abnormally low blood pressure, or rapid heart rate and elevated blood pressure may occur. Headache, dizziness, muscle spasms and profound weakness are common. Alterations of level of consciousness, anxiety, paralysis, seizures and coma may occur. Seizures may be more common in children.
   Ingestion
Vomiting, diarrhea, fecal incontinence and abdominal pain may occur.
   Inhalation
Dyspnea, rales, bronchorrhea, or tachypnea may be noted. Pulmonary edema may occur in severe cases.
   Skin
Sweating is a consistent but not universal sign.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur in severe poisonings. Opsoclonus has occurred rarely. Excessive salivation commonly occurs.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Systemic effects can occur from dermal exposure to organophosphates. Remove contaminated clothing, wash skin, hair and nails vigorously with repeated soap washings. Leather absorbs pesticides; all contaminated leather should be discarded. Rescue personnel and bystanders should avoid direct contact with contaminated skin, clothing, or other objects. Treatment should include recommendations listed in the oral exposure section when appropriate. Some chemicals can produce systemic poisoning by absorption through intact skin. Carefully observe patients with dermal exposure for the development of any systemic signs or symptoms and administer symptomatic treatment as necessary. Contraindications - succinylcholine and other cholinergic agents are contraindicated.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved. Suction oral secretions until atropinization. Treatment should include recommendations listed in the oral exposure section when appropriate. Contraindications - succinylcholine and other cholinergic agents are contraindicated.

Transport.
UN number
3018
Response guide
Hazard class
6.1
Packing Group
I; II; III