Dimethyl sulfate

  • Sulfuric acid, dimethyl ester
  • Dimethyl monosulfate
  • DMS
Formula
(CH3)2SO4
Structure
Description
Colorless, oily liquid, faint onion odor.
Uses
Formerly as war gas, manufacture of dyes, colors, perfumes, solvent for separation of mineral oils, analysis of auto fluids.

Registry Numbers and Inventories.
CAS
77-78-1
EC (EINECS/ELINCS)
201-058-1
EC Index Number
016-023-00-4
EC Class
Carcinogenic Category 2; Mutagenic Category 3; Very toxic; Toxic; Corrosive; Sensitising
R 45 E25 E26 34 43 68
RTECS
WS8225000
RTECS class
Tumorigen; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
1595
Merck
12,3305
Beilstein/Gmelin
635994
Beilstein Reference
4-01-00-01251
RCRA
U103
Swiss Giftliste 1
G-1564
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H6O4S
Formula mass
126.13
Melting point, °C
-31.8
Boiling point, °C
189
Vapor pressure, mmHg
0.85 (25 C)
Vapor density (air=1)
4.35
Saturation Concentration
660 ppm (0.06%) at 20 C (calculated)
Density
1.349 g/cm3 (0 C)
Solubility in water
28 g/L
Surface tension
40.12 g/s2 (18 C)
Refractive index
1.3861 (15.8 C)
Partition coefficient, pKow
0.08
Heat of vaporization
40.7 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Do not store in metal containers.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong bases, ammonia, and moist air or water. Can react violently with ammonium hydroxide and sodium azide.
Decomposition
Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
83
Autoignition, °C
450
Upper exp. limit, %
23.2
Lower exp. limit, %
3.6
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Combustible Liquid. Contact with metals may evolve flammable hydrogen gas. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. For small fires, use dry chemical, carbon dioxide, sand, earth, water spray or regular foam. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Moderately flammable. Requires moderate heating.
Hazards
Material is normally stable even under fire exposure conditions and is not hazardously reactive with water. It is incompatible with strong oxidizers and strong ammonia solutions.
Combustion products
Combustion may produce irritants and toxic gases.
Health
4
 
Flammability
2
 
 
Reactivity
1
 

Health.
Exposure limit(s)
OSHA PEL: TWA 1 ppm (5 mg/m3) skin NIOSH REL: Ca TWA 0.1 ppm (0.5 mg/m3) skin See Appendix A NIOSH IDLH: Potential occupational carcinogen 7 ppm
Carcinogin
G-A3, I-2A, N-2, CP65
Poison_Class
1*
Exposure effects
May cause liver and kidney damage. May cause cancer in humans. May cause reproductive and fetal effects.
   Ingestion
Harmful if swallowed. Causes gastrointestinal tract burns. Effects may be delayed 2 to 4 hours.
   Inhalation
May be fatal if inhaled. Effects may be delayed. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. May cause lung damage. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
   Skin
Causes skin burns.
   Eyes
Causes eye burns. May cause irreversible eye injury.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1595
Response guide
Hazard class
6.1
PRTC
T
Packing Group
I
 
USCG CHRIS Code
DSF
 
HS Code
2920 90 10
 
Std. Transport #
4921405