Dimethylglyoxime

  • Diacetyl dioxime
  • Biacetyl dioxime
  • 2,3-Diisonitrosobutane
  • 2,3-Butanedione, dioxime
  • Chugaev's reagent
Formula
(CH3CNOH)2
Structure
Description
White to off-white powder. Perceptible odor.
Uses
Detection and determination of Ni and its separation from Co and many other metals.

Registry Numbers and Inventories.
CAS
95-45-4
EC (EINECS/ELINCS)
202-420-1
R 20/22
S 22 36/37
RTECS
EK2975000
RTECS class
Agricultural Chemical and Pesticide; Mutagen
Merck
13,3272
Beilstein/Gmelin
506731
Beilstein Reference
3-01-00-03105
Swiss Giftliste 1
G-4553
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H8N2O2
Formula mass
116.12
Melting point, °C
240 - 241
Boiling point, °C
53 (8 torr)
Vapor density (air=1)
4
Density
1.37 g/cm3
Solubility in water
Soluble
pKa/pKb
10.27 (pKa)

Hazards and Protection.
Storage
Keep away from heat and flame. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.
Disposal code
3
Stability
Stable under normal temperatures and pressures. May violently decompose at temperatures above 190 C.
Incompatibilities
Strong oxidizing agents, strong reducing agents, strong acids.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Prolonged or repeated skin contact may cause dermatitis. Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May cause irritation of the mucous membranes.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2928 00 90