- Nitrogen tetroxide
- Nitrogen oxide
- Nitrogen peroxide
Red-brown liquid with a sharp, unpleasant chemical odor.
Intermediate in nitric acid & sulfuric acid production, in nitration of organic compound & explosives, in manufacture of oxidized cellulose compound (hemostatic cotton), has been used to bleach flour, proposed as oxidizing agent in rocket propulsion nitrogen dioxide.
Registry Numbers and Inventories.
EC Index Number
Very toxic; Corrosive
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
123.4 (-10.9 C)
Vapor density (air=1)
1.43958 g/cm3 (21.64 C)
Solubility in water
0.418 cp (20 C)
27.5 g/s2 at 19.8 C
Heat of fusion
Heat of vaporization
Hazards and Protection.
Store in a cool, dry, well ventilated location. Separate from oxidizable materials. Outside or detached storage is preferred.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Wear special protective clothing and positive pressure self-contained breathing apparatus.
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode.
Neutralizing Agents for Acids and Caustics: Flush with water, then use soda ash or lime.
Reacts with reducing agents to generate heat and products that may be gaseous (causing pressurization of closed containers) Reacts with alkalis to form nitrates and nitrites Reacts explosively with liquid ammonia even at very low temperatures (below its freezing point) Reacts energetically with boron trichloride Mixtures with metal carbonyls are hypergolic (enflame immediately) Mixtures with halocarbons, hydrazine derivatives, heterocyclic bases (pyridine), isopropyl nitrite/propyl nitrite, active metals (magnesium, calcium, etc.), nitroaromatics, nitrogen trichloride, phosphorus, triethylamine, unsaturated hydrocarbons
When heated to decomposition it emits toxic fumes of oxides of nitrogen.
Fire Extinguishing Agents: Stop flow of gas
Substance does not burn but will support combustion.
When heated to decomposition, toxic fumes of nitrogen oxides are emitted. May ignite other combustible materials (wood, paper, oil, etc.). Mixture with fuels may explode. Container may explode in heat of fire. Vapor explosion and poison hazard may occur indoors, outdoors or in sewers. Decomposes in water, forming nitric acid and nitric oxide. Avoid moisture and physical damage to storage container. Incompatible with combustible matter, chlorinated hydrocarbons, ammonia, carbon disulfide. Reacts with alkalies to form nitrates and nitrites. Violent reaction with cyclohexane, fluorine, formaldehyde, alcohols, nitrobenzene, petroleum, and toluene.
Produces toxic gas when heated.
Fatigue, restlessness, anxiety, mental confusion, lethargy, and loss of consciousness may be noted.
Nausea, vomiting and abdominal pain may develop.
Nitrogen oxides react with water in the respiratory tract to slowly form nitric and nitrous acid. Cough, hyperpnea and dyspnea will be seen. Rapid and shallow respirations, mild or violent coughing and physical signs of pulmonary edema may develop. Pulmonary edema may be delayed 4 to 24 hours.
Cyanosis may occur.
Inflammation of the eye may occur.
Seek medical assistance.
Remove patient to fresh air and have him breathe as deeply as possible; call a doctor; enforce complete rest for 24-48 hours; keep warm; give oxygen if coughing starts; physician may administer morphine (10 mg.)
Flush with water for at least 15 min.
Immediately flush with running water for at least 20 minutes. Effects may be delayed.
USCG CHRIS Code
Std. Transport #