Dipropylene glycol methyl ether

  • Dipropylene glycol monomethyl ether
  • Dowanol 50b
  • (2-Methoxymethylethoxy)propanol
Formula
(CH3O)C3H6OC3H6(OH)
Structure
Description
Clear colorless liquid with a mild ethereal odor in moderate concentrations. May be a lachrymator as is the chemically related propylene glycol monomethyl ether.
Uses
In manufacture of various cosmetics.

Registry Numbers and Inventories.
CAS
34590-94-8
EC (EINECS/ELINCS)
252-104-2
RTECS
JM1575000
RTECS class
Primary Irritant
Merck
12,3407
Beilstein/Gmelin
NA
EPA OPP
11508
Swiss Giftliste 1
G-1590
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H16O3
Formula mass
148.20
Melting point, °C
-80
Boiling point, °C
190
Vapor pressure, mmHg
0.4 (25 C)
Vapor density (air=1)
5.11
Saturation Concentration
0.05% (500 ppm) at 25 C (calculated)
Evaporization number
0.02 (butyl acetate = 1)
Density
0.951 g/cm3 (20 C)
Solubility in water
Miscible
Viscosity
3.5 cp @ 25C
Surface tension
28.8 g/s2
Refractive index
1.419 (25 C)

Hazards and Protection.
Storage
In general, toxic materials or that can decompose into toxic components should be stored in cool ventilated place, out of sun, away from fire hazard. Substance must be periodically inspected and monitored. Incompatible materials should be isolated.
B3
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Protective gloves and clothing. Safety goggles.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Stop discharge if possible. Call fire department. Avoid contact with liquid. Isolate and remove discharged material. Notify local health and pollution control agencies. Evacuate areas. Should be removed. Chemical and physical treatment. Effect of low concentrations on aquatic life is unknown. May be dangerous if it enters water intakes. Notify local health and wildlife officials. Notify operators of nearby water intakes.
Disposal code
1
Stability
Volatile.
Incompatibilities
May react violently with strong oxidizing agents.

Fire.
Flash Point,°C
79
Autoignition, °C
205
Upper exp. limit, %
14
Lower exp. limit, %
1.1
Fire fighting
Extinguish with dry chemical, alcohol foam, or carbon dioxide. Cool exposed containers with water.
Fire potential
This material is combustible.
Hazards
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 100 ppm; 606 mg/m3 (skin) (ACGIH 1991-1992). OSHA PEL: TWA 100 ppm (600 mg/m3) skin NIOSH REL: TWA 100 ppm (600 mg/m3) ST 150 ppm (900 mg/m3) skin NIOSH IDLH: 600 ppm
Poison_Class
5
Exposure effects
CNS depression was reported in dogs given 6 ml/kg iv. No toxicity was noted when 5 ml/kg was given orally.
   Inhalation
Dipropylene glycol has little vapor hazard at ordinary temperatures.
   Skin
Dry skin. Defats the skin. See inhalation. May be absorbed through the skin.
   Eyes
Redness, pain.

First aid
 
   Ingestion
Treatment is symptomatic and supportive. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
USCG CHRIS Code
DPY
 
40 Glycol ethers
HS Code
2909 49 19
 
IMO Chemical Code
18
IMO Pollution Category
D