Disopyramide

  • Lispine
  • a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide
  • 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)butyramide
  • a-Diisopropylaminoethyl-a-phenylpyridine-2-acetamide
Formula
C21H29N3O
Structure
Uses
Sodium channel blocker

Registry Numbers and Inventories.
CAS
3737-09-5
EC (EINECS/ELINCS)
223-110-2
RTECS
UR8432000
RTECS class
Drug; Reproductive Effector; Human Data
Merck
12,3424
Beilstein/Gmelin
492056
Beilstein Reference
5-22-14-00172
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C21H29N3O
Formula mass
339.48
Melting point, °C
80
Vapor pressure, mmHg
2E-10 (25 C)
Solubility in water
Slightly soluble
pKa/pKb
3.90 (pKb)
Heat of vaporization
77.5 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Acids, Bases, Oxidizing agents.
Decomposition
Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.

Fire.
Flash Point,°C
259
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Harmful if swallowed. Target organ(s): Female reproductive system. Heart.
   Ingestion
Harmful if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.