(±)-Dropropizine

  • Catabex
  • Ditustat
  • Dopropizin
  • 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)
  • Katril
  • Larylin
Formula
C13H20N2O2
Structure
Uses
Cough suppressant.

Registry Numbers and Inventories.
CAS
17692-31-8
EC (EINECS/ELINCS)
241-683-7
RTECS
TZ1074800
RTECS class
Drug
Merck
12,3507
Beilstein/Gmelin
615737
Beilstein Reference
5-23-02-00111
Austrailia AICS
Listed
Korea ECL
Listed

Properties.
Formula
C13H20N2O2
Formula mass
236.31
Melting point, °C
107
Boiling point, °C
431
Vapor pressure, mmHg
3E-8 (25 C)
Solubility in water
Slightly soluble
pKa/pKb
7.46 (pKb)
Heat of vaporization
72.3 kJ/mol

Hazards and Protection.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.

Fire.
Flash Point,°C
237
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful if swallowed.
   Ingestion
Harmful if swallowed.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.