Echinomycin

  • Echinomycin A
  • NSC-526417
  • Quinomycin A
  • S-426-S (Lepetit)
Formula
C51H64N12O12S2
Description
Very faintly beige powder.

Registry Numbers and Inventories.
CAS
512-64-1
R: 23/24/25 46
S: 36/37/39 45 53
RTECS
JW5250000
UN (DOT)
3462
Merck
12,3545
Beilstein/Gmelin
78671
Beilstein Reference
4-27-00-09726

Properties.
Formula
C51H64N12O12S2
Formula mass
1101.27
Melting point, °C
217 - 218
Density
1.41 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
9.38 (pKa)
Partition coefficient, pKow
-0.67

Hazards and Protection.
Storage
Keep container tightly closed. Store at 2 - 8 C.
Protection
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Oxides of carbon, nitrogen and sulfur.

Fire.
Fire fighting
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Extinguishing media: Water spray. Carbon dioxide, dry chemical powder or appropriate foam.
Combustion products
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Toxic. May cause heritable genetic damage. Toxic by inhalation, in contact with skin and if swallowed. Nausea, headache, and vomiting. Reversible liver enzyme abnormalities.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
3462
Response guide
Hazard class
6.1
Packing Group
II