Epibromohydrin

  • 1-Bromo-2,3-epoxypropane
Formula
C3H5BrO
Structure
Description
A colorless volatile liquid.
Uses
Sporicide.

Registry Numbers and Inventories.
CAS
3132-64-7
EC (EINECS/ELINCS)
221-525-3
R 23/24/25 34 40
S 26 36/37/39 45
RTECS
TX4115000
RTECS class
Mutagen
UN (DOT)
2558
Beilstein/Gmelin
79786
Beilstein Reference
5-19-01-00552
Canada DSL/NDSL
NDSL
US TSCA
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C3H5BrO
Formula mass
136.99
Melting point, °C
-40
Boiling point, °C
135
Vapor pressure, mmHg
2
Vapor density (air=1)
4.72
Density
1.6148 g/cm3 (14 C)
Solubility in water
Reacts
Refractive index
1.4761 (10 C)
Partition coefficient, pKow
0.85

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Flammables-area. Refrigerator (approx 4 C).
Handling
Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not get water inside containers. A vapor suppressing foam may be used to reduce vapors.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, aluminum, magnesium, sodium, strong oxidizing agents, zinc, water.
Decomposition
Carbon monoxide, carbon dioxide, hydrogen bromide.

Fire.
Flash Point,°C
56
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
4
 
Flammability
2
 
 
Reactivity
2
 

Health.
Exposure effects
Abnormally low blood pressure and apnea have been reported in animal studies. CNS depression has been the primary cause of death in poisoned laboratory animals. Fetotoxicity was seen in mice.
   Ingestion
May be fatal if swallowed. May cause irritation of the digestive tract and possible burns.
   Inhalation
May be fatal if inhaled. May cause respiratory tract irritation. Vapors may cause dizziness or suffocation.
   Skin
May be fatal if absorbed through the skin. May cause severe irritation and possible burns.
   Eyes
May cause severe eye irritation. May cause eye burns. Lachrymator.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting only when instructed to do so by a physician.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2558
Response guide
Hazard class
6.1
Packing Group
I
 
Std. Transport #
4921013