Ergosta-5,7,9(11),22-tetraen-3-ol, (3b,22E)

  • Dehydroergosterol
  • Ergosta-5,7,9(11),22-tetraen-3b-ol
  • 9(11)-Dehydroergosterol
Formula
C28H42O
Structure
Uses
A fluorescent cholesterol analog useful as a probe in membrane research.

Registry Numbers and Inventories.
CAS
516-85-8
Merck
12,2925

Properties.
Formula
C28H42O
Formula mass
394.64
Melting point, °C
146
Boiling point, °C
521
Vapor pressure, mmHg
5E-13 (25 C)
Density
1.02 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
14.89 (pKa)
Partition coefficient, pKow
8.91
Heat of vaporization
91.33 kJ/mol

Hazards and Protection.
Storage
Store at -20 C. Keep containers tightly closed. Store under inert atmosphere.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable if stored at recommended conditions.
Incompatibilities
Strong oxidizing agents, Bases.
Decomposition
Carbon monoxide, Carbon dioxide, Hydrogen chloride gas, Phosgene gas.

Fire.
Flash Point,°C
221
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed. Irritating to eyes and skin. Limited evidence of a carcinogenic effect. Target organs: Liver. Kidneys. Eyes. Heart. Central nervous system. Cardiovascular system. Blood. May cause nervous system disturbances. Exposure to and/or consumption of alcohol may increase toxic effects.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.