Erythromycin ethylsuccinate

  • Succinic acid, monoester with erythromycin
  • Erythromycin, 2'-(ethyl butanedioate)
  • Eritrocina
  • Monomycin
  • Paediathrocin
  • Oxacyclotetradecane, erythromycin deriv.
Formula
C43H75NO16
Structure
Description
Crystals.
Uses
Medication.

Registry Numbers and Inventories.
CAS
1264-62-6
EC (EINECS/ELINCS)
215-033-8
RTECS
WM9800000
RTECS class
Drug; Human Data
Beilstein/Gmelin
77638
Beilstein Reference
4-18-00-07416
Austrailia AICS
Listed

Properties.
Formula
C43H75NO16
Formula mass
862.06
Melting point, °C
109 - 110
Solubility in water
Insoluble
pKa/pKb
6.42 (pKb)

Hazards and Protection.
Storage
Keep in a cool, dry, well-ventilated area in a sealed container.
Handling
Keep container closed when not in use. Avoid contact. Follow label directions.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Where environmental controls are lacking or in an enclosed space, use a NIOSH/MSHA approved respirator for dust.
Small spills/leaks
Ventilate area. Use protective eqiupment. Sweep or vacuum up. Do not creat dust. Place in a dry container for disposal. Clean spill area with water.
Stability
Stable.
Incompatibilities
Strong oxidizing agents.
Decomposition
None reported.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
Allergic skin and respiratory reactions have been reported.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.