Erythroxyanthraquinone

  • 1-Hydroxy-9,10-anthraquinone
  • 1-Hydroxy-9,10-anthracenedione
Formula
C14H8O3
Structure
Description
Red-orange to fine yellow crystals
Uses
1-Hydroxyanthraquinone can be used as an intermediate in the production of dyes and drugs.

Registry Numbers and Inventories.
CAS
129-43-1
EC (EINECS/ELINCS)
204-946-7
RTECS
CB7178000
RTECS class
Tumorigen; Mutagen; Primary Irritant
Beilstein/Gmelin
1912751
Beilstein Reference
4-08-00-02586
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C14H8O3
Formula mass
224.22
Melting point, °C
192-194
Boiling point, °C
415
Vapor pressure, mmHg
1.8E-7 (25 C)
Solubility in water
0.5 mg/L (25 C)
pKa/pKb
7.15 (pKa)
Heat of vaporization
69.4 kJ/mol

Hazards and Protection.
Storage
Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required need to be carried. Carcinogens should be kept in only one section of storage cabinet, explosion-proof refrigerator or freezer that bears appropriate label.
Protection
During manufacture, wear protective suits (preferably disposable, one-piece and close-fitting at ankles and wrists), gloves hair covering and overshoes. In s chemical laboratory, gloves and gowns should always be worn. However, gloves should not be assumed to provide full protection.
Respirators
Carefully fitted masks or respirators may be necessary when working with particulates or gases.
Small spills/leaks
Material should be collected and placed or collected in proper containers for disposal. The lid should be secured and the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface is not contaminated
Decomposition
Emits acrid smoke and fumes when heated to decomposition.

Fire.
Flash Point,°C
219

Health.
Carcinogin
I-2B
Exposure effects
   Inhalation
Causes irritation.
   Skin
Causes irritation.
   Eyes
Causes irritation.

First aid
 
   Ingestion
Rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool.
   Inhalation
Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary. Monitor for shock and treat if necessary. Anticipate seizures and treat if necessary
   Skin
Cover skin burns with dry sterile dressings after decontamination.
   Eyes
Flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport to medical facility.

Transport.