Esculetin

  • Esculetol
  • Cichoriin aglycon
  • Aesculetin
  • Cichorigenin
  • 6,7-Dihydroxycoumarin
  • 6,7-Dihydroxy-2H-1-benzopyran-2-one
Formula
C9H6O4
Structure
Description
Yellow crystalline powder.
Uses
Substance is used in filters for absorption of ultraviolet light.

Registry Numbers and Inventories.
CAS
305-01-1
EC (EINECS/ELINCS)
206-161-5
R 36/37/38
RTECS
GN6382500
RTECS class
Drug; Natural Product
UN (DOT)
1759
Merck
13,3731
Beilstein/Gmelin
152788
Beilstein Reference
5-18-03-00202

Properties.
Formula
C9H6O4
Formula mass
178.14
Melting point, °C
267
Boiling point, °C
470
Vapor pressure, mmHg
2E-9 (25 C)
Solubility in water
Soluble
pKa/pKb
8.63 (pKa)
Partition coefficient, pKow
0.55
Heat of vaporization
76.0 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
201
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
   Ingestion
The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. The toxicological properties of this substance have not been fully investigated.
   Skin
No information regarding skin irritation and other potential effects was found.
   Eyes
No information regarding eye irritation and other potential effects was found.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1759
Response guide
Hazard class
8
Packing Group
I; II; III