Esfenvalerate

  • s-5620a alpha
  • S-1844
  • S-5602-alpha
  • Asana
  • (S)-alpha-Cyano-3-phenoxybenzyl (S)-2-(4-Chlorophenyl)-3-methylbutyrate
  • 4-Chloro-2-(1-methylethyl)benzeneacetate
Formula
C25H22ClNO3
Structure
Description
Viscous yellow or brown liquid.
Uses
Control of a wide range of insect pests on cotton, maize, groundnuts, soya beans, sugar cane, sunflowers, sorghum, fruit trees, vegetables, ornamentals, and noncrop land.

Registry Numbers and Inventories.
CAS
66230-04-4
EC Index Number
650-033-00-5
RTECS
CY1576367
RTECS class
Agricultural Chemical and Pesticide; Tumorigen
Beilstein/Gmelin
4275674
EPA OPP
109303
Swiss Giftliste 1
G-87739
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C25H22ClNO3
Formula mass
419.93
Melting point, °C
59-60
Boiling point, °C
539
Vapor pressure, mmHg
1E-11 (25 C)
Density
1.163 g/cm3 (23 C)
Solubility in water
< 1 mg/L (20 C)
Partition coefficient, pKow
7.45
Heat of vaporization
81.6 kJ/mol

Hazards and Protection.
Storage
Pyrethrins with piperonyl butoxide topical preparations should be stored in well-closed containers at a temperature less than 40C, preferably between 15-30C.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Employees should be provided with and required to use dust- and splash-proof safety goggles where pyrethroids may contact the eyes. Employees should be provided with and be required to use impervious clothing, gloves, and face shields (eight-inch minimum). Wear appropriate equipment to prevent: repeated or prolonged skin contact. Wear eye protection to prevent: reasonable probability of eye contact.
Respirators
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure mode. Any supplied-air respirator with a full face piece and operated in pressure-demand or other positive pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive pressure mode.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Pyrethrins are stable for long periods in water-based aerosols where emulsifiers give neutral water systems.
Incompatibilities
Avoid contact with strong oxidizers. Incompatible with lime and ordinary soaps because acids and alkalies speed up processes of hydrolysis.

Fire.
Flash Point,°C
280
Fire fighting
Use carbon dioxide, foam, or dry chemical on fires involving pyrethroids.
Fire potential
Pyrethrins. Burn with difficulty.

Health.
Poison_Class
3
Exposure effects
   Ingestion
Nausea, vomiting and abdominal pain commonly occur and develop within 10 to 60 minutes following ingestion.
   Inhalation
Hypersensitivity reactions characterized by pneumonitis, cough, dyspnea, wheezing, chest pain, and bronchospasm may occur. Rare cases of respiratory failure and cardiopulmonary arrest have been reported.
   Skin
Irritant and contact dermatitis may develop. Erythema which mimics sunburn has also been noted after prolonged repeated exposure.

First aid
 
   Ingestion
There is no specific antidote for pyrethrin poisoning. Treatment is symptomatic and supportive and includes monitoring for the development of hypersensitivity reactions with respiratory distress. Provide adequate airway management when needed. Gastric decontamination is usually not required unless the pyrethrin product is combined with a hydrocarbon. Allergic reaction: mild: antihistamines with or without epinephrine. Severe: oxygen, aggressive airway management, antihistamines, epinephrine (adult: 0.3 To 0.5 Ml of a 1:1000 solution subcutaneously; child: 0.01 Ml/kg; may repeat in 20 to 30 min), corticosteroids, ecg monitoring, and iv fluids.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Vitamin e topical application is highly effective in relieving paresthesias.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.