Estazolam

  • Somnatrol
  • Cannoc
  • 8-Chloro-6-phenyl-4H-S-triazolo[4,3-a][1,4]benzodiazepine
  • 8-Chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Formula
C16H11ClN4
Structure
Uses
Hypnotic. US DEA Schedule IV.

Registry Numbers and Inventories.
CAS
29975-16-4
EC (EINECS/ELINCS)
249-982-4
36/37/38
36/37/39
RTECS
XZ5473500
RTECS class
Tumorigen; Drug; Reproductive Effector
Merck
12,3744
Beilstein/Gmelin
1220868
Beilstein Reference
6-26
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C16H11ClN4
Formula mass
294.74
Melting point, °C
224 - 227
Boiling point, °C
490
Vapor pressure, mmHg
1E-9 (25 C)
Solubility in water
Insoluble
pKa/pKb
12.33 (pKb)
Heat of vaporization
75.6 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Wear respirator, chemical safety goggles, rubber boots, and heavy rubber gloves.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
250
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Irritant. Irritating to eyes, respiratory system and skin. Target organ(s): Central nervous system.
   Ingestion
May be harmful if swallowed.
   Inhalation
Material is irritating to mucous membranes and upper
   Skin
Causes skin irritation. May be harmful if absorbed through the skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Transport.