Estradiol, 3-benzoate

  • Benovocylin
  • Benzhormovarine
  • Benzo gynoestryl
  • Benzoestrofol
  • Benzofoline
Formula
C25H28O3
Structure
Description
Colorless, brown or white solid.

Registry Numbers and Inventories.
CAS
50-50-0
EC (EINECS/ELINCS)
200-043-7
RTECS
KG4050000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Hormone
Beilstein/Gmelin
3107526
Beilstein Reference
4-09-00-00406
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C25H28O3
Formula mass
376.49
Melting point, °C
341
Density
1.225 g/cm3
Partition coefficient, pKow
5.78

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong bases.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water fog, dry chemical, carbon dioxide, or regular foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.