Ethchlorvynol

  • Ethyl chlorvynol
  • Alvinol
  • Arvynol
  • 1-Chloro-3-ethyl-1-penten-4-yl-3-ol
  • 5-Chloro-3-ethylpent-1-yn-4-en-3-ol
  • 1-Chloro-3-ethylpent-1-4-yn-3-ol
Formula
C7H9ClO
Structure
Description
Colorless to yellow liquid. Pungent aromatic odor.
Uses
Medication.

Registry Numbers and Inventories.
CAS
113-18-8
RTECS
SB4725000
RTECS class
Drug; Reproductive Effector; Human Data
Merck
12,3774
Beilstein/Gmelin
1702245
Beilstein Reference
4-01-00-02315
Japan ENCS (MITI)
Listed

Properties.
Formula
C7H9ClO
Formula mass
144.6
Boiling point, °C
28.5 - 30 (0.1 torr)
Density
1.064 g/cm3 (20 C)
Solubility in water
immiscible
Refractive index
1.478 (25 C)
pKa/pKb
12.05 (pKa)

Hazards and Protection.
Storage
Capsules should be stored in tight, light-resistant containers and have an expiration date of 3 years following the date of manufacture.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Slowly darkens on exposure to light and air.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
blurred vision, facial numbness, lethargy, headache, prolonged coma, hypothermia, dysarthria, and areflexia may be noted. Concurrent ingestion of alcohol or other sedative hypnotics will enhance the toxic effects of ethchlorvynol. Neonatal withdrawal following maternal abuse has been reported.
   Ingestion
Ausea and vomiting are common.
   Inhalation
Respiratory depression and non-cardiogenic pulmonary edema (most common following IV injection) may be noted.
   Skin
Bullous eruptions have been described following an overdose.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.