Ethisterone

  • 17a-Ethynyltestosterone
  • 17b-Hydroxy-4,17a-pregnen-20-yn-3-one
  • 4,17a-Pregnen-17b-ol-20-yn-3-one
  • Anhydrohydroxyprogesterone
  • Ethynyltestosterone
  • Progestoral
Formula
C21H28O2
Structure
Description
White crystalline powder
Uses
A testosterone derivative with effects similar to progestational

Registry Numbers and Inventories.
CAS
434-03-7
EC (EINECS/ELINCS)
207-096-5
22 24/25
RTECS
TU5570250
RTECS class
Reproductive Effector; Human Data; Hormone
UN (DOT)
2811
Merck
12,3787
Beilstein/Gmelin
1889895
Beilstein Reference
4-08-00-01225
Korea ECL
Listed

Properties.
Formula
C21H28O2
Formula mass
312.45
Melting point, °C
201 - 205
Boiling point, °C
446
Vapor pressure, mmHg
8E-10 (25 C)
Solubility in water
Soluble.
pKa/pKb
13.11 (pKa)
Heat of vaporization
81.3 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
190
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Toxic. Harmful by inhalation, in contact with skin and if swallowed. May cause harm to the unborn child. Target organ(s): Female reproductive system. Nerves.
   Ingestion
See Inhalation.
   Inhalation
TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Transport.
UN number
2811
Response guide
Hazard class
6.1