Ethyl acetate

  • Acetic acid, ethyl ester
  • Acetoxy ethane
  • Acetic ether
Formula
CH3COOC2H5
Structure
Description
Clear, colorless liquid with a fruity odor.
Uses
Solvent.

Registry Numbers and Inventories.
CAS
141-78-6
EC (EINECS/ELINCS)
205-500-4
EC Index Number
607-022-00-5
EC Class
Highly flammable; Irritant; Repeated exposure may cause skin dryness or cracking; Vapours may cause drowsiness and dizziness
R 11 36 66 67
S 16 26 33
RTECS
AH5425000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Human Data; Primary Irritant
UN (DOT)
1173
Merck
13,3792
Beilstein/Gmelin
506104
Beilstein Reference
4-02-00-00127
RCRA
U112
EPA OPP
44003
Swiss Giftliste 1
G-1157
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H8O2
Formula mass
88.11
Melting point, °C
-83
Boiling point, °C
77.1
Vapor pressure, mmHg
91 (25 C)
Vapor density (air=1)
3.04
Saturation Concentration
9.6% at 20 C
Evaporization number
6.0 (butyl acetate=1)
Odor Threshold Odor threshold 0.006 - 0.686 mg/L
Critical temperature
250
Critical pressure
38.0
Density
0.902 g/cm3 (20 C)
Solubility in water
0.016 g/L (25 C)
Viscosity
0.428 cp (25 C)
Surface tension
23.6 g/s2 (20 C)
Refractive index
1.3719 (20 C)
Dipole moment
1.78 D (20 C)
Dielectric constant
6 (25 C)
Partition coefficient, pKow
0.73
Heat of fusion
9.4 kJ/mol
Heat of vaporization
35.6 kJ/mol
Heat of combustion
-2288 kJ/mol

Hazards and Protection.
Storage
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas.
B2
Handling
Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
A full facepiece respirator with organic vapor cartridge may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.
Small spills/leaks
Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Disposal code
1
Stability
Stable under normal shipping and handling conditions.
Incompatibilities
Chlorosulfonic acid, lithium aluminum hydride + 2-chloromethylfuran, lithium tetrahydroaluminate, oleum, potassium t-butoxide. Substance coming in contact with nitrates or strong acids/oxidizers/alkalies may cause fire.
Decomposition
Oxides of carbon.

Fire.
Flash Point,°C
-4
Autoignition, °C
426
Upper exp. limit, %
11.5
Lower exp. limit, %
2.1
Fire fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use alcohol foam, dry chemical or carbon dioxide.
Fire potential
Highly flammable liquid and vapor.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 400 ppm; 1440 mg/m3 A4 (ACGIH 1997). OSHA PEL: TWA 400 ppm (1400 mg/m3) NIOSH REL: TWA 400 ppm (1400 mg/m3) NIOSH IDLH: 2000 ppm LEL
Poison_Class
5
Exposure effects
Chronic inhalation may cause effects similar to those of acute inhalation. Chronic exposure may produce anemia, leukocytosis, cloudy swelling, and fatty degeneration of the viscera.
   Ingestion
Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation. Inhalation of high concentrations may cause narcotic effects. Exposure Inhalation can cause severe irritation of mucous membranes and upper respiratory tract. Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. High concentrations may cause lung damage. An irritant to the nose, throat, and upper respiratory tract. Exposure to high concentrations have a narcotic effect and may cause liver and kidney damage.
   Skin
Causes irritation to skin. Symptoms include redness, itching, and pain. Repeated or prolonged contact with the skin has a defatting effect and may cause dryness, cracking, and possibly dermatitis.
   Eyes
Causes eye irritation. Vapors may cause eye irritation. Repeated exposure may cause conjunctival irritation and corneal clouding.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
1173
Response guide
Hazard class
3
Packing Group
II
 
USCG CHRIS Code
ETA
 
HS Code
2915 31 00
 
Std. Transport #
4909160
 
IMO Chemical Code
18
IMO Pollution Category
D