Ethyl acetoacetate

  • Ethyl acetylacetate
  • Acetoacetic acid ethyl ester
Formula
CH3COCH2COOC2H5
Structure
Description
Colorless liquid, fruity rum odor.
Uses
Flavoring agent in food.

Registry Numbers and Inventories.
CAS
141-97-9
EC (EINECS/ELINCS)
205-516-1
EC Class
irritant
R 36/38
RTECS
AK5250000
RTECS class
Drug; Mutagen; Primary Irritant
UN (DOT)
1993
Merck
13,3793
Beilstein/Gmelin
385838
Beilstein Reference
4-03-00-01528
Swiss Giftliste 1
G-1028
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H10O3
Formula mass
130.14
Melting point, °C
-45
Boiling point, °C
180.8
Vapor pressure, mmHg
0.89 (25 C)
Vapor density (air=1)
4.48
Saturation Concentration
1000 ppm at 20 C (calculated)
Evaporization number
0.1 (butyl acetate=1)
Density
1.0188 g/cm3 (20 C)
Solubility in water
116 g/L
Viscosity
1.73 cp (20 C)
Surface tension
33.93 g/s2 (20 C)
Refractive index
1.41937 (20 C)
pKa/pKb
10.69 (pKa)
Partition coefficient, pKow
0.72
Heat of vaporization
41.7 kJ/mol
Heat of combustion
-2435 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from heat and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
B3 D2B
Handling
Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. A vapor suppressing foam may be used to reduce vapors.
Disposal code
1
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
70
Autoignition, °C
295
Upper exp. limit, %
9.5
Lower exp. limit, %
1.4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Water or foam may cause frothing. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation. Vapors may cause dizziness or suffocation.
   Skin
Causes moderate skin irritation.
   Eyes
Causes moderate eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1993
Response guide
Hazard class
3
Packing Group
I; II; III
 
USCG CHRIS Code
EAA
 
HS Code
2918 30 00
 
Std. Transport #
4915419
 
IMO Chemical Code
18
IMO Pollution Category
D