Ethyl amyl ketone

  • 3-Octanone
  • Amyl ethyl ketone
  • Octan-3-one
Formula
CH3(CH2)4COCH2CH3
Structure
Description
Colorless liquid, mild fruity odor.
Uses
Fragrance ingredient.

Registry Numbers and Inventories.
CAS
106-68-3
EC (EINECS/ELINCS)
203-423-0
EC Class
flammable
R 10 36/38
RTECS
RH1485000
RTECS class
Primary Irritant
UN (DOT)
2271
Merck
13,3799
Beilstein/Gmelin
1700021
Beilstein Reference
4-01-00-03341
Swiss Giftliste 1
G-1161
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H16O
Formula mass
128.22
Melting point, °C
-18.5
Boiling point, °C
168
Vapor pressure, mmHg
2 (25 C)
Vapor density (air=1)
4.4
Saturation Concentration
2632 ppm (0.3%) at 25 C (calculated)
Evaporization number
0.3 (Butyl acetate = 1)
Density
0.8502 g/cm3 (0 C)
Solubility in water
Slightly soluble
Viscosity
0.9 mPas 20 C
Surface tension
26.21 g/s2 (25 C)
Refractive index
1.4133 (20 C)
Partition coefficient, pKow
2.50
Heat of vaporization
40.6 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
46
Autoignition, °C
330
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
Moderate fire hazard.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Vapor may travel considerable distance to a source of ignition and flash back.
Health
1
 
Flammability
3
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Limited studies have generally documented little or no effect of ketones on reproduction in experimental animals. Human data is lacking. 2,5-Hexanedione has an effect on spermatogenesis in male experimental animals.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Vapors may cause dizziness or suffocation.
   Skin
May cause moderate skin irritation. The toxicological properties of this material have not been fully investigated.
   Eyes
May cause eye irritation. The toxicological properties of this material have not been fully investigated.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2271
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
EAK
 
HS Code
2914 19 90
 
Std. Transport #
4912224
 
IMO Pollution Category
C
IMO Hazard code
P