Ethyl chloroacetate

  • Chloroacetic acid, ethyl ester
  • Ethyl chloroethanoate
Formula
CH2ClCOOC2H5
Structure
Description
Water-white, mobile liquid, extremely irritating, pungent, fruity odor, lachrymator.
Uses
Solvent, organic synthesis, military poison, vat dyestuffs.

Registry Numbers and Inventories.
CAS
105-39-5
EC (EINECS/ELINCS)
203-294-0
EC Index Number
607-070-00-7
EC Class
Toxic; Dangerous for the Environment
R 23/24/25 50
S 7/9 45 61
RTECS
AF9110000
RTECS class
Tumorigen; Primary Irritant
UN (DOT)
1181
Merck
13,3818
Beilstein/Gmelin
506455
Beilstein Reference
4-02-00-00481
Swiss Giftliste 1
G-2000
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C4H7ClO2
Formula mass
122.55
Melting point, °C
-26
Boiling point, °C
144
Vapor pressure, mmHg
5 (25 C)
Vapor density (air=1)
4.23-4.46
Saturation Concentration
13160 ppm (1.3%) at 37.5 C (calculated)
Evaporization number
0.23 (20 C) (diethyl ether = 1)
Critical temperature
345
Critical pressure
37.4
Density
1.15 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
2.93x10-3 pa.s @ 247.15 K
Surface tension
31.7 g/s2 (21 C)
Refractive index
1.4235 (20 C)
Partition coefficient, pKow
0.94
Heat of vaporization
49.4 kJ/mol
Heat of combustion
-2044 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Flammables-area.
Handling
Wash thoroughly after handling. Do not allow water to get into the container because of violent reaction. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Do not allow contact with water. Use only in a chemical fume hood. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not expose spill to water. A vapor suppressing foam may be used to reduce vapors.
Disposal code
9
Stability
Combines vigorously or explosively with water. Volatile in steam.
Incompatibilities
Strong oxidizing agents, strong reducing agents, strong acids, strong bases.
Decomposition
Hydrogen chloride, phosgene, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
54
Autoignition, °C
452
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. May ignite or explode on contact with steam or moist air. Extinguishing media: Use water spray to cool fire-exposed containers. DO NOT USE WATER! For large fires, use water spray, fog or alcohol-resistant foam. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Contact professional fire-fighters immediately.
Fire potential
Flammable liquid; a dangerous fire hazard when exposed to heat or flame.
Hazards
Vapors form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
Combustion products
Irritating, toxic hydrogen chloride and phosgene may be generated in fires.
Health
3
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
1
Exposure effects
Possible cancer hazard based on tests with laboratory animals. Halogenated acid ester compounds have the potential to produce pulmonary edema.
   Ingestion
Harmful if swallowed. Causes digestive tract irritation.
   Inhalation
Causes respiratory tract irritation. Vapors may cause dizziness or suffocation. Harmful if inhaled.
   Skin
Causes skin irritation. Harmful if absorbed through the skin.
   Eyes
Causes severe eye irritation. Lachrymator.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1181
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
ECA
 
HS Code
2915 40 00
 
Std. Transport #
4912014