Ethyl cyanoacetate

  • Cyanoacetic acid, ethyl ester
  • Cyanoacetic ester
  • Ethyl cyanoethanoate
  • Malonic acid, ethyl ester nitrile
Formula
CNCH2COOC2H5
Structure
Description
Colorless to pale straw-colored liquid, slight, pleasant odor, lachrymator.
Uses
Organic synthesis, pharmaceuticals, dyes.

Registry Numbers and Inventories.
CAS
105-56-6
EC (EINECS/ELINCS)
203-309-0
S 26 37/39
RTECS
AG4110000
RTECS class
Other
UN (DOT)
2666
Merck
13,3821
Beilstein/Gmelin
605871
Beilstein Reference
4-02-00-01889
Swiss Giftliste 1
G-7089
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C5H7NO2
Formula mass
113.12
Melting point, °C
-22
Boiling point, °C
209
Vapor pressure, mmHg
0.28 (25 C)
Vapor density (air=1)
3.9
Saturation Concentration
1316 ppm (0.1%) at 67.8 C (calculated)
Density
1.063 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
0.97 cp (79.7 C)
Surface tension
34.91 g/s2 (18 C)
Refractive index
1.4166 (15 C)
pKa/pKb
3.19
Partition coefficient, pKow
0.06
Heat of vaporization
44.0 kJ/mol
Heat of combustion
-2636 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Provide ventilation.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong reducing agents, strong acids, strong bases.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
84
Autoignition, °C
460
Upper exp. limit, %
10.6
Lower exp. limit, %
1.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Substance may react with water, and may release corrosive and/or toxic gases. Extinguishing media: Use dry chemical or carbon dioxide. Contact with water or steam may produce toxic and flammable vapors.
Fire potential
May burn but does not ignite readily.
Hazards
Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
1
 
 
Reactivity
1
 

Health.
Poison_Class
3
Exposure effects
Initially, headache, vertigo, and agitation occur, followed by combative behavior, coma, seizures, and death.
   Ingestion
May cause irritation of the digestive tract.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation. Lachrymator.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2666
Response guide
Hazard class
6.1
Packing Group
III
 
HS Code
2926 90 95
 
Std. Transport #
4925189