Ethyl diazoacetate

  • Diazoacetic ester
  • Ethyl 2-diazoethanoate
  • Ethoxycarbonyldiazomethane
Formula
NN+CHCOOC2H5
Structure
Uses
Reagent for ruthenium-catalyzed asymmetric cyclopropanation of alkenes.

Registry Numbers and Inventories.
CAS
623-73-4
EC (EINECS/ELINCS)
210-810-8
5 10 22
RTECS
AG5775000
RTECS class
Tumorigen
UN (DOT)
1992
Merck
13,3021
Beilstein/Gmelin
107654
Beilstein Reference
4-03-00-01495
Swiss Giftliste 1
G-5286
New Zealand
Listed

Properties.
Formula
C4H6N2O2
Formula mass
114.1
Melting point, °C
-22
Boiling point, °C
48 - 50
Density
1.0909 g/mL (20 C)
Surface tension
31.5 g/s2 (21 C)
Refractive index
1.45971 (20 C)

Hazards and Protection.
Storage
Keep tightly closed. Keep away from combustible materials, heat, sparks, and open flame. Store at 2-8 C
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Cover with dry-lime, sand, or soda ash. Place in covered containers using non-sparking tools and transport outdoors. Ventilate area and wash spill site after material pickup is complete.
Stability
Potentially explosive, especially in large scale at hight temperature. Use protective shielding.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
27
Fire fighting
Extinguish using Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Emits toxic fumes under fire conditions. Flammable liquid. Specific Method(s) of Fire Fighting: Use water spray to cool fire-exposed containers.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
1*
Exposure effects
Heating may cause an explosion. Flammable. Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Irritant. Neurological hazard. Possible carcinogen/
   Ingestion
See inhalation.
   Inhalation
May be fatal. May cause irritatior or burns. Vapors may cause dizziness or suffocation.
   Skin
Causes skin irritation. Multiple Routes: Harmful if swallowed, inhaled, or absorbed through skin. Vapor or mist is irritating to the eyes, mucous
   Eyes
See inhalation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Transport.
UN number
1992
Response guide
Hazard class
3
Packing Group
II