Ethyl hydroxyacetate

  • Ethyl glycolate
  • Acetic acid, hydroxy-, ethyl ester
  • Glycolic acid, ethyl ester
Formula
C4H8O3
Structure
Description
Clear, colorless liquid.

Registry Numbers and Inventories.
CAS
623-50-7
EC (EINECS/ELINCS)
210-798-4
RTECS
MC5410000
RTECS class
Primary Irritant
UN (DOT)
1760
Beilstein/Gmelin
1743766
Beilstein Reference
4-03-00-00580
Canada DSL/NDSL
DSL
US TSCA
Listed
Korea ECL
Listed

Properties.
Formula
C4H8O3
Formula mass
104.10
Boiling point, °C
157
Vapor pressure, mmHg
1 (25 C)
Vapor density (air=1)
3.6
Density
1.1078 g/cm3 (0 C)
Solubility in water
Very soluble
Refractive index
1.418 (20 C)
pKa/pKb
13.14 (pKa)
Partition coefficient, pKow
-0.54
Heat of vaporization
45.8 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
62
Fire fighting
Extinguish using agent most appropriate for surrounding fire.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cyanosis, characterized by bluish skin.
   Inhalation
May cause cyanosis, characterized by bluish-colored skin. Causes respiratory tract irritation.
   Skin
Causes skin irritation. Absorption into the body may cause cyanosis.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1760
Response guide
Hazard class
8
Packing Group
I; II; III