Ethyl isoamyl ketone

  • Ethyl isoamyl ketone
  • 6-Methyl-3-heptanone
Formula
C8H16O
Structure
Uses
Solvent.

Registry Numbers and Inventories.
CAS
624-42-0
EC (EINECS/ELINCS)
210-844-3
UN (DOT)
1224
Beilstein/Gmelin
1741782
Beilstein Reference
4-01-00-03344
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H16O
Formula mass
128.21
Melting point, °C
-59
Boiling point, °C
164
Critical temperature
325
Critical pressure
26.9
Density
0.8304 g/cm3 (20 C)
Solubility in water
insoluble
Refractive index
1.4209 (20 C)
Partition coefficient, pKow
2.67

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Make no contact with the spilled material. ELIMINATE all ignition sources and ground all equipment. Stop leak if you can do it without risk. A vapor suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean non-sparking tools to collect absorbed material.
Stability
No data.

Fire.
Fire fighting
Use of water spray when fighting fire may be inefficient. Small Fires: Dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Large Fires: Water spray, fog or alcohol-resistant foam. Use water spray or fog; do not use straight streams.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Limited studies have generally documented little or no effect of ketones on reproduction in experimental animals. Human data is lacking. 2,5-Hexanedione has an effect on spermatogenesis in male experimental animals.
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Ingestion of significant amounts may cause respiratory depression. Pulmonary aspiration may result in chemical pneumonitis.
   Skin
Skin exposure to the liquid or vapor may result in dermatitis and paresthesias of affected areas. Contact urticaria has also been reported.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
1224
Response guide
Hazard class
3
Packing Group
I; II; III