Ethyl isocyanatoacetate

  • Isocyanatoacetic acid ethyl ester
  • Ethoxycarbonylmethyl isocyanate
  • Carbethoxymethyl isocyanate
  • Acetic acid, isocyanato-, ethyl ester
Formula
C5H7NO3
Structure
Description
Liquid

Registry Numbers and Inventories.
CAS
2949-22-6
EC (EINECS/ELINCS)
220-967-4
R 20/22 36/37/38 42
S 23 26 36/37/39 45
RTECS
AI4450000
RTECS class
Other
UN (DOT)
2924
Beilstein/Gmelin
970503
Beilstein Reference
4-04-00-02428
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C5H7NO3
Formula mass
129.13
Boiling point, °C
182
Vapor pressure, mmHg
1.4 (25 C)
Critical temperature
367
Critical pressure
33.5
Density
1.151 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.4251 (20 C)
Partition coefficient, pKow
1.46
Heat of vaporization
41.8 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, bases, alcohols, amines.
Decomposition
Hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
72
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Combustible Liquid. Containers may explode when heated. Extinguishing media: Use dry chemical or carbon dioxide.
Fire potential
Flammable/combustible material. May be ignited by heat, sparks or flames.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2924
Response guide
Hazard class
3
Packing Group
I; II; III