Ethyl isothiocyanate

  • Ethyl mustard oil
  • Isothiocyanatoethane
  • Isothiocyanic acid, ethyl ester
Formula
C2H5NCS
Structure
Description
Clear, colorless liquid. Sulfide odor.
Uses
Military poison gas.

Registry Numbers and Inventories.
CAS
542-85-8
EC (EINECS/ELINCS)
208-831-2
EC Class
flammable, irritant
R 10 23/24/25 34 42
S 23 26 36/37/39 45
RTECS
NX8590000
RTECS class
Mutagen
UN (DOT)
3080
Merck
13,3848
Beilstein/Gmelin
1737705
Beilstein Reference
4-04-00-00403
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C3H5NS
Formula mass
87.14
Melting point, °C
-6
Boiling point, °C
130 - 132
Vapor pressure, mmHg
11 (25 C)
Vapor density (air=1)
3.00
Density
1.0192 g/cm3 (0 C)
Solubility in water
Slightly soluble
Surface tension
35.02 g/s2 (18.4 C)
Refractive index
1.5142 (20 C)
Partition coefficient, pKow
1.47
Heat of vaporization
35.4 kJ/mol
Heat of combustion
-2529 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.
Handling
Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not allow contact with water. Wash clothing before reuse. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not get water inside containers. A vapor suppressing foam may be used to reduce vapors.
Disposal code
9
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Moisture.
Decomposition
Hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrocarbons.

Fire.
Flash Point,°C
32
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure effects
May cause liver and kidney damage. Effects may be delayed. May cause lung damage. Repeated or prolonged exposure may cause allergic reactions in sensitive individuals. Inhalation of product may aggravate existing chronic repiratory problems such as asthma, emphysema or bronchitis.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. The toxicological properties of this substance have not been fully investigated. Ingestion of large amounts may cause CNS depression.
   Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Exposure produces central nervous system depression. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. At high concentrations, isocyanates affect mucous membranes of the respiratory tract and may lead to fatal pulmonary edema. Exposure to low and often even unmeasurable isocyanate concentration results in sensitization. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions. May cause burning sensation in the chest.
   Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause irritation and dermatitis. May cause cyanosis of the extremities.
   Eyes
Causes eye irritation. May cause conjunctivitis, ulceration and turbidity of the cornea. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
3080
Response guide
Hazard class
6.1
Packing Group
II
 
HS Code
2930 90 70