Ethyl methanesulfonate

  • Ethyl mesylate
  • O-Ethyl methylsulfonate
  • Methanesulfonic acid, ethyl ester
  • EMS
Formula
CH3SO2OCH2CH3
Structure
Description
Clear colorless liquid.
Uses
Biochemical research.

Registry Numbers and Inventories.
CAS
62-50-0
EC (EINECS/ELINCS)
200-536-7
R 45 46 20/21/22
RTECS
PB2100000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector
UN (DOT)
2810
Merck
13,3859
Beilstein/Gmelin
773969
Beilstein Reference
4-04-00-00012
RCRA
U119
Swiss Giftliste 1
G-6687
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C3H8O3S
Formula mass
124.16
Boiling point, °C
213
Vapor pressure, mmHg
0.34
Density
1.2079 g/cm3 (20 C)
Solubility in water
Soluble
Refractive index
1.4194 (15 C)
Partition coefficient, pKow
0.09

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong bases.
Decomposition
Carbon monoxide, oxides of sulfur, carbon dioxide.

Fire.
Flash Point,°C
100
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use agent most appropriate to extinguish fire.
Fire potential
This chemical is combustible.
Health
-
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OSHA: Possible Select carcinogen
Carcinogin
I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
May cause cancer according to animal studies.
   Ingestion
May cause irritation of the digestive tract.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2810
Response guide
USCG CHRIS Code
EMS