Ethylene glycol dibutyl ether

  • Di-n-butoxyethane
  • Dibutyl cellosolve
  • 1,2-Dibutoxyethane
  • 1,1'-(1,2-Ethanediylbis(oxy))bis-butane
Formula
C10H22O2
Structure
Description
Colorless liquid.

Registry Numbers and Inventories.
CAS
112-48-1
EC (EINECS/ELINCS)
203-976-8
RTECS
KH9450000
RTECS class
Primary Irritant
Beilstein/Gmelin
1738358
Beilstein Reference
4-01-00-02382
Swiss Giftliste 1
G-1894
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C10H22O2
Formula mass
174.32
Melting point, °C
-69
Boiling point, °C
195 - 196
Vapor pressure, mmHg
0.4 (25 C)
Vapor density (air=1)
6
Density
0.836 g/cm3 (19 C)
Solubility in water
Slightly soluble
Refractive index
1.4139 (19 C)
Partition coefficient, pKow
2.75
Heat of vaporization
42.3 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Protective gloves. Safety goggles.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
May react violently with strong oxidizing agents.

Fire.
Flash Point,°C
51
Fire fighting
Fire Extinguishing Agents Not to Be Used: Water may be ineffective.Fire Extinguishing Agents: Dry chemical, alcohol foam, carbon dioxide.
Hazards
On decomposition, it emits acrid smoke and irritating fumes.
Combustion products
On decomposition, it emits acrid smoke and irritating fumes.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Coma has been described after ingestion of 30 to 100 ml of pure glycol ethers in adults.
   Ingestion
Hemorrhagic gastritis was seen in a case of fatal poisoning with methyl ether.
   Inhalation
Ards was reported in one case after ingestion of 500 ml of 9.1% Ethylene glycol butyl ether (egbe).
   Skin
Redness, pain, dry skin. May be absorbed through the skin.
   Eyes
Eye irritation is generally slight, but may be severe with the propyl ether.

First aid
 
   Ingestion
Emesis is contraindicated due to rapid gi absorption and potential for rapid progression to coma. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Correct severe acidosis (ph < 7.1) With iv nahco3. 1 To 2 meq/kg is a useful starting dose. Monitor abgs. Ethanol (etoh) may inhibit the formation of toxic metabolites, but there are no controlled human studies documenting efficacy. Loading dose - administer 7.6 To 10 ml/kg of 10% etoh in d5w iv over 30 minutes. Maintenance dose - administer 1.39 Ml/kg/hr of 10% etoh in d5w by iv infusion. Aim at achieving and maintaining 100 to 130 mg/dl blood ethanol levels.
   Inhalation
Call for medical aid. Remove from exposure
   Skin
Wash with copious amounts of water.
   Eyes
Flush with water for at least 15 minutes.

Transport.
USCG CHRIS Code
EGB
 
40 Glycol ethers
IMO Chemical Code
#
IMO Pollution Category
[D]