Ethylene glycol dinitrate
- Glycol dinitrate
- 1,2-Ethanediol, dinitrate
Colorless to yellow, oily. Liquid. Odorless.
Plasticizer (nitrocellulose explosives).
Registry Numbers and Inventories.
EC Index Number
Explosive; Very toxic; Danger of cumulative effects
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
0.48 (25 C)
Vapor density (air=1)
1.5053 g/cm3 (0 C)
Solubility in water
8.06 cp (0.2 C)
1.4519 (7.7 C)
Partition coefficient, pKow
Heat of fusion
Heat of vaporization
Heat of combustion
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Wear appropriate eye protection and protective clothing to prevent skin and eye contact. Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Strong oxidizing agents.
Decomposes violently upon heating or impact with a force similar to that of nitroglycerin. See nitrates on decomposition, emits toxic fumes nitrates.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
TLV: 0.05 ppm; 0.31 mg/m3 (as TWA) (skin) ACGIH 1992-1993). OSHA PEL: C 0.2 ppm (1 mg/m3) skin NIOSH REL: ST 0.1 mg/m3 skin NIOSH IDLH: 75 mg/m3
Abnormally low blood pressure is common. Low heart rate may occur in predisposed patients; reflex rapid heart rate may occur. Death occurs secondary to circulatory collapse or respiratory failure. Headache and dizziness are common, even after administration of therapeutic doses. Acute wernicke's encephalopathy from intravenous infusions may be precipitated by ethanol and propylene glycol diluents. In male rats, a dominant lethal test showed no effect on male fertility; interstitial cell tumors of rat testes were induced after nitroglycerin exposure. Results on teratogenicity in rats are conflicting.
Nausea, vomiting, colicky pain, and diarrhea may occur.
LOSS OF VISION - A transient loss of vision reportedly occurred before acute toxic effects from nitroglycerin exposure. Constriction of the pupil and corneal damage occurred after intravenous exposure.
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.