Ethylene glycol dinitrate

  • Glycol dinitrate
  • Nitroglycol
  • 1,2-Ethanediol, dinitrate
Formula
O2NOCH2CH2ONO2
Structure
Description
Colorless to yellow, oily. Liquid. Odorless.
Uses
Plasticizer (nitrocellulose explosives).

Registry Numbers and Inventories.
CAS
628-96-6
EC (EINECS/ELINCS)
211-063-0
EC Index Number
603-032-00-9
EC Class
Explosive; Very toxic; Danger of cumulative effects
RTECS
KW5600000
RTECS class
Other
Merck
12,3846
Beilstein/Gmelin
1709055
Beilstein Reference
4-01-00-02413
Swiss Giftliste 1
G-2647
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H4N2O6
Formula mass
152.06
Melting point, °C
-22.3
Boiling point, °C
199
Vapor pressure, mmHg
0.48 (25 C)
Vapor density (air=1)
5.24
Density
1.5053 g/cm3 (0 C)
Solubility in water
Slightly soluble
Viscosity
8.06 cp (0.2 C)
Refractive index
1.4519 (7.7 C)
Partition coefficient, pKow
1.16
Heat of fusion
19.1 kJ/mol
Heat of vaporization
41.8 kJ/mol
Heat of combustion
-1122 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate eye protection and protective clothing to prevent skin and eye contact. Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Decomposes violently upon heating or impact with a force similar to that of nitroglycerin. See nitrates on decomposition, emits toxic fumes nitrates.

Fire.
Flash Point,°C
104
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure limit(s)
TLV: 0.05 ppm; 0.31 mg/m3 (as TWA) (skin) ACGIH 1992-1993). OSHA PEL: C 0.2 ppm (1 mg/m3) skin NIOSH REL: ST 0.1 mg/m3 skin NIOSH IDLH: 75 mg/m3
Poison_Class
1
Exposure effects
Abnormally low blood pressure is common. Low heart rate may occur in predisposed patients; reflex rapid heart rate may occur. Death occurs secondary to circulatory collapse or respiratory failure. Headache and dizziness are common, even after administration of therapeutic doses. Acute wernicke's encephalopathy from intravenous infusions may be precipitated by ethanol and propylene glycol diluents. In male rats, a dominant lethal test showed no effect on male fertility; interstitial cell tumors of rat testes were induced after nitroglycerin exposure. Results on teratogenicity in rats are conflicting.
   Ingestion
Nausea, vomiting, colicky pain, and diarrhea may occur.
   Eyes
LOSS OF VISION - A transient loss of vision reportedly occurred before acute toxic effects from nitroglycerin exposure. Constriction of the pupil and corneal damage occurred after intravenous exposure.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
Hazard class
Forbidden