Ethylene glycol monoethyl ether

  • 2-Ethoxyethanol
  • Glycol ethyl ether
  • Cellosolve
Formula
C2H5OCH2CH2OH
Structure
Description
Colorless liquid, mild pleasant, sweetish, ethereal odor.
Uses
Solvent for nitrocellulose, lacquers and dopes, incr stability of emulsions, used in varnish removers, cleansing soln, dye baths, finishing leather with water pigments and dye soln.

Registry Numbers and Inventories.
CAS
110-80-5
EC (EINECS/ELINCS)
203-804-1
EC Index Number
603-012-00-X
EC Class
Flammable; Toxic for reproduction Category 2; Harmful
R 60 61 10 20/21/22
RTECS
KK8050000
RTECS class
Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
1171
Merck
13,3786
Beilstein/Gmelin
1098271
Beilstein Reference
4-01-00-02377
RCRA
U359
Swiss Giftliste 1
G-1186
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H10O2
Formula mass
90.12
Melting point, °C
-70
Boiling point, °C
135
Vapor pressure, mmHg
3.8 (20 C)
Vapor density (air=1)
3.1
Saturation Concentration
0.5% at 20 C
Evaporization number
0.32 (butyl acetate = 1)
Odor Threshold Odor threshold >255 ppm
Critical temperature
312
Critical pressure
43.5
Density
0.932 g/cm3 (20 C)
Solubility in water
Miscible
Viscosity
2.14 cp (20 C)
Surface tension
28.2 g/s2 @ 25 C
Refractive index
1.406 (20 C)
Dipole moment
2.08 D
Dielectric constant
11.9 (20 C)
Partition coefficient, pKow
-0.32
Heat of vaporization
40.53 kJ/mol
Heat of combustion
-2695 kJ/mol

Hazards and Protection.
Storage
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static spark.
B3 D1B D2A
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A half-face organic vapor respirator may be worn for up to ten times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Remove all sources of ignition. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizers, strong acids, strong bases, copper, aluminum.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
43
Autoignition, °C
235
Upper exp. limit, %
15.7
Lower exp. limit, %
1.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Flammable liquid and vapor.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Toxic gases, such as carbon monoxide, may be produced in fire.
Health
2
 
Flammability
2
 
 
Reactivity
3
 

Health.
Exposure limit(s)
OSHA PEL: TWA 200 ppm (740 mg/m3) skin NIOSH REL: TWA 0.5 ppm (1.8 mg/m3) skin NIOSH IDLH: 500 ppm
Poison_Class
2
Exposure effects
Prolonged exposure may cause injury to bone marrow, blood cells, kidney, liver and reproductive system. A suspected human reproductive and birth defect hazard.
   Ingestion
May cause nausea, vomiting, abdominal pain, breathing difficulties, weakness. Liver and kidney damage may result from swallowing large quantities of the material.
   Inhalation
Causes irritation to the respiratory tract. Symptoms may include sore throat, coughing, headache, nausea and shortness of breath. High concentrations have a narcotic effect.
   Skin
May cause irritation with redness and pain. May be absorbed through the skin with possible systemic effects.
   Eyes
Vapors are irritating and may produce immediate pain, redness and tearing. Splashes can cause severe pain, stinging, swelling.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1171
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
EEO
 
40 Glycol ethers
HS Code
2909 44 00
 
Std. Transport #
4912016
 
IMO Chemical Code
17
IMO Pollution Category
D
IMO Hazard code
S