Etodolac

  • Etodolic acid
  • Ultradol
  • AY-24236
  • 1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
  • 1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
  • Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl
Formula
C17H21NO3
Structure

Registry Numbers and Inventories.
CAS
41340-25-4
R: 23/24/25 40
S: 22 36 45
RTECS
UQ0360000
Merck
12,3920
Canada DSL/NDSL
DSL
New Zealand
Listed

Properties.
Formula
C17H21NO3
Formula mass
287.36
Melting point, °C
145 - 148
Boiling point, °C
508
Vapor pressure, mmHg
3.9E-11 (25 C)
Density
1.193 g/cm3 (20 C)
Solubility in water
Slightly soluble
pKa/pKb
4.31 (pKa)
Partition coefficient, pKow
3.59
Heat of vaporization
81.8 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Chemical resistant gloves, safety goggles.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, carbon dioxide, and nitrogen oxides.

Fire.
Fire fighting
EXTINGUISHING MEDIA Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Combustion products
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Toxic by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Possible teratogen. Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals. Gastrointestinal disturbances. Exposure can cause: Nausea, dizziness, and headache.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.