Fenthion

  • O,O-Dimethyl-O-(4-methylthio-m-tolyl) phosphorothioate
  • Phosphorothioic acid, O,O-dimethyl O-(3-methyl-4-(methylthio)phenyl) ester
Formula
C10H15O3PS2
Structure
Description
Yellow to tan oily liquid with a slight odor of garlic.
Uses
The material is used as an insecticide, avicide.

Registry Numbers and Inventories.
CAS
55-38-9
EC (EINECS/ELINCS)
200-231-9
EC Index Number
015-048-00-8
EC Class
Mutagenic Category 3; Toxic; Harmful; Dangerous for the Environment
RTECS
TF9625000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data
UN (DOT)
3018
Merck
12,4044
Beilstein/Gmelin
1974129
EPA OPP
53301
Swiss Giftliste 1
G-10482
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C10H15O3PS2
Formula mass
278.33
Melting point, °C
6.1
Boiling point, °C
330
Vapor pressure, mmHg
0.0003 (25 C)
Density
1.250 g/cm3 (20 C)
Solubility in water
60 mg/L
Refractive index
1.5698 (20 C)
Partition coefficient, pKow
4.091
Heat of vaporization
55.0 kJ/mol

Hazards and Protection.
Storage
Under normal conditions fenthion is stable and can be stored a long time. It is stable to 210 C and is resistant to light. Also resists alkali to pH 9.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
If you spill this chemical, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
Stable to light thermally stable up to 210 C stable under normal use conditions. Subject to hydrolysis. 50% Hydrolysis at 80 C in acid medium requires 36 hr, or 95 min in alkaline medium.
Incompatibilities
May react with strong reducing agents such as hydrides to generate highly toxic and flammable phosphine gas.
Decomposition
When heated to decomposition it emits very toxic fumes of phosphorus oxides and sulfur oxides.

Fire.
Flash Point,°C
153
Fire fighting
Fires involving this material can be cntrolled with a dry chemical. carbon dioxide, foam or Halon extinguisher.
Fire potential
This compound is probably combustible.
Hazards
Containers may explode when heated.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure limit(s)
TLV: ppm; 0.2 mg/m3 (as TWA) (skin) (ACGIH 1993-1994). NIOSH REL: See Appendix D
Poison_Class
3
Exposure effects
Reduced body temperature or elevated body temperature may occur. Low heart rate and abnormally low blood pressure may develop after moderate to severe poisoning. Rapid heart rate, elevated blood pressure, and changes in respiratory rate may also occur. Early giddiness, anxiety headache, and restlessness followed by ataxia, drowsiness, and confusion are common with moderate to severe exposures. Sporadic reports of human birth defects related to organophosphates have not been fully verified.
   Ingestion
Nausea, vomiting, abdominal cramps, and diarrhea are common muscarinic effects. Both painless and frank clinical pancreatitis have been reported.
   Inhalation
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Effects of contact or inhalation may be delayed.
   Skin
Profuse sweating is common. Pallor may be noted. Dermal sensitization has been reported.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur. Salivation commonly occurs.

First aid
 
   Ingestion
CHOLINESTERASE INHIBITORS ARE EXTREMELY TOXIC AND FAST-ACTING POISONS. IMMEDIATELY call a hospital of poison control center and transport the victim to a hospital. Atropine is an antidote for cholinesterase inhibitors but should only be administered by properly trained personnel. In the absence of this option and if the victim is conscious and not convulsing, it may be worth considering the risk of inducing vomiting, even though the induction of vomiting is not usually recommended outside of a physician's care. Ipecac syrup or salt water may be used to induce vomiting in such an emergency. If the victim is convulsing or unconscious, do not give anything by mouth, assure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
3018
Response guide
Hazard class
6.1
Packing Group
I; II; III