Fludarabine

  • 9-beta-D-Arabinofuranosyl-2-fluoroadenine
  • 2-Fluoroadenine-9-b-D-arabinofuranoside
  • 9-beta-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine
Formula
C10H12FN5O4
Structure
Uses
Used to treat chronic lymphocytic leukemia

Registry Numbers and Inventories.
CAS
21679-14-1
EC (EINECS/ELINCS)
244-525-5
20/21/22 36/37/38 63
22 26 36
RTECS
AU6207000
RTECS class
Mutagen
Merck
13,4152
Beilstein/Gmelin
1225932
Beilstein Reference
6-26

Properties.
Formula
C10H12FN5O4
Formula mass
285.23
Melting point, °C
265 - 267
Vapor pressure, mmHg
2E-23 (25 C)
Solubility in water
Very soluble
pKa/pKb
13.05 (pKa)
Heat of vaporization
114.3 kJ/mol

Hazards and Protection.
Storage
Store at 2-8 C.

Fire.
Flash Point,°C
406

Health.
Exposure effects
Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.

First aid
 

Transport.