Flumethiazide

  • Trifluoromethylthiazide
  • Ademol
  • 4H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-(trifluoromethyl)-, 1,1-dioxide
  • 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-(trifluoromethyl)-, 1,1-dioxide
  • 6-Trifluoromethyl-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide
  • 7-Sulfamoyl-6-trifluoromethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Formula
C8H6F3N3O4S2
Structure
Uses
Diuretic, antihypertensive agent.

Registry Numbers and Inventories.
CAS
148-56-1
EC (EINECS/ELINCS)
205-717-4
RTECS
DK9800000
RTECS class
Drug
Merck
12,4174
Beilstein/Gmelin
45925
Beilstein Reference
4-27-00-08037

Properties.
Formula
C8H6F3N3O4S2
Formula mass
329.28
Melting point, °C
305 - 307
Boiling point, °C
529
Vapor pressure, mmHg
3E-11 (25 C)
Solubility in water
Insoluble
pKa/pKb
9.06 (pKa)
Heat of vaporization
80.4 kJ/mol

Hazards and Protection.

Fire.
Flash Point,°C
274

Health.
Exposure effects
Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.

First aid
 

Transport.