Fluoroacetyl chloride

  • 2-Fluoroacetyl chloride
Formula
C2H2ClFO
Structure

Registry Numbers and Inventories.
CAS
359-06-8
EC (EINECS/ELINCS)
206-623-6
RTECS
AO6825000
RTECS class
Other
Beilstein/Gmelin
1739051
Beilstein Reference
4-02-00-00454
Canada DSL/NDSL
NDSL
US TSCA
Listed
New Zealand
Listed

Properties.
Formula
C2H2ClFO
Formula mass
96.48
Boiling point, °C
65 - 71
Density
1.353 g/cm3 (20 C)
Solubility in water
Soluble
Refractive index
1.3831 (20 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors (may react violently with water). Small spills: absorb with sand or other non-combustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal.
Stability
No data.
Incompatibilities
May react vigorously or explosively

Fire.
Fire fighting
(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Spray cooling water on containers that are exposed to flames until well after fire is out. Move container from fire area if you can do so without risk. Do not get water in container, as material may react violently with water.(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam.

Health.
Exposure effects
Respiratory depression, reduced body temperature, rapid heart rate, and abnormally low blood pressure may occur. Apprehension, diaphoresis, disorientation, agitation, paresthesias, muscle twitching, hyperactive behavior, tingling, coma, and convulsions may develop.
   Ingestion
Nausea, vomiting, hypersalivation, abdominal or epigastric pain, and diarrhea may be seen.
   Inhalation
Respiratory depression and cyanosis may develop. Death may be due to hypoxia and respiratory depression during seizures.
   Skin
Fluoroacetyl chloride is irritating or corrosive to the skin.
   Eyes
Blurred vision, facial paresthesias, and hypersalivation may be noted. FLUOROACETYL CHLORIDE is irritating or corrosive to the eyes.

First aid
 
   Ingestion
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Systemic absorption - there is little evidence that fluoroacetate can be absorbed systemically in toxic amounts through intact skin. Should systemic symptoms develop following dermal contact with this material: treatment should include recommendations listed in the inhalation exposure section when appropriate. Irritation - treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Systemic toxicity - there is no evidence that fluoroacetate can be absorbed in toxic quantities following ocular exposure. Should systemic symptoms develop following exposure by this route - treatment should include recommendations listed in the inhalation exposure section when appropriate. Irritation/consultation - fluoracetyl chloride - may be irritating or corrosive to the eye. If serious irritation or corneal burns are present, prolonged initial flushing and early ophthalmologic consultation are advisable.

Transport.
USCG CHRIS Code
FLC