- 2-Fluoroacetyl chloride
Registry Numbers and Inventories.
Boiling point, °C
65 - 71
1.353 g/cm3 (20 C)
Solubility in water
1.3831 (20 C)
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors (may react violently with water). Small spills: absorb with sand or other non-combustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal.
May react vigorously or explosively
(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Spray cooling water on containers that are exposed to flames until well after fire is out. Move container from fire area if you can do so without risk. Do not get water in container, as material may react violently with water.(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam.
Respiratory depression, reduced body temperature, rapid heart rate, and abnormally low blood pressure may occur. Apprehension, diaphoresis, disorientation, agitation, paresthesias, muscle twitching, hyperactive behavior, tingling, coma, and convulsions may develop.
Nausea, vomiting, hypersalivation, abdominal or epigastric pain, and diarrhea may be seen.
Respiratory depression and cyanosis may develop. Death may be due to hypoxia and respiratory depression during seizures.
Fluoroacetyl chloride is irritating or corrosive to the skin.
Blurred vision, facial paresthesias, and hypersalivation may be noted. FLUOROACETYL CHLORIDE is irritating or corrosive to the eyes.
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Systemic absorption - there is little evidence that fluoroacetate can be absorbed systemically in toxic amounts through intact skin. Should systemic symptoms develop following dermal contact with this material: treatment should include recommendations listed in the inhalation exposure section when appropriate. Irritation - treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Systemic toxicity - there is no evidence that fluoroacetate can be absorbed in toxic quantities following ocular exposure. Should systemic symptoms develop following exposure by this route - treatment should include recommendations listed in the inhalation exposure section when appropriate. Irritation/consultation - fluoracetyl chloride - may be irritating or corrosive to the eye. If serious irritation or corneal burns are present, prolonged initial flushing and early ophthalmologic consultation are advisable.
USCG CHRIS Code