Fluorometholone

  • Oxylone
  • Delmeson
  • 21-Desoxy-9a-fluoro-6-methylprednisolone
  • 6a-Methyl-9a-fluoro-21-desoxyprednisolone
  • 11b,17a-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
  • 9a-Fluoro-11b,17a-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione
Formula
C22H29FO4
Structure
Uses
Medication to control inflammation of eye tissue.

Registry Numbers and Inventories.
CAS
426-13-1
EC (EINECS/ELINCS)
207-041-5
20/21/22
RTECS
TU3834100
RTECS class
Drug
Merck
12,4213
Beilstein/Gmelin
3172388
Beilstein Reference
4-08-00-03006
Canada DSL/NDSL
DSL
Austrailia AICS
Listed

Properties.
Formula
C22H29FO4
Formula mass
376.47
Melting point, °C
292 - 303
Vapor pressure, mmHg
3E-13 (25 C)
Solubility in water
Insoluble
pKa/pKb
12.42 (pKa)
Heat of vaporization
92/2 kJ/mol

Hazards and Protection.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, Strong acids, Acid chlorides, Acid anhydrides.
Decomposition
Carbon monoxide, Carbon dioxide, Hydrogen fluoride.

Fire.
Flash Point,°C
273
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful. Harmful by inhalation, in contact with skin and if swallowed. Target organ(s): Eyes.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.