Flurandrenolide

  • Fluorandrenolone
  • Cordran
  • Drenison
  • Drocort
  • Fluorandrenolone
  • 6a-Fluoro-11b,16a,17,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide
Formula
C24H33FO6
Structure
Uses
Used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions.

Registry Numbers and Inventories.
CAS
1524-88-5
EC (EINECS/ELINCS)
216-196-8
RTECS
TU5024800
RTECS class
Drug; Mutagen; Hormone
Merck
12,4232
Beilstein/Gmelin
1442935
Beilstein Reference
5-19-06-00547
Austrailia AICS
Listed

Properties.
Formula
C24H33FO6
Formula mass
436.52
Melting point, °C
209 - 219
Boiling point, °C
579
Vapor pressure, mmHg
8E-16 (25 C)
Solubility in water
Insoluble
pKa/pKb
12.84 (pKa)
Heat of vaporization
99.5 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Hydrogen fluoride.

Fire.
Flash Point,°C
304
Fire fighting
Extinguish using Noncombustible. Use extinguishing media appropriate to surrounding fire conditions. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. Readily absorbed through skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Transport.