Flurbiprofen

  • 3-Fluoro-4-phenylhydratropic acid
  • BTS-18322
  • 2-(2-Fluoro-4-biphenylyl)propionic acid
  • 2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid
  • 2-Fluoro-alpha-methyl-4-biphenylacetic acid
Formula
C15H13FO2
Structure
Uses
Non-steroidal anti-inflammatory agent with antifungal activity.

Registry Numbers and Inventories.
CAS
5104-49-4
EC (EINECS/ELINCS)
225-827-6
36/37/39 45
RTECS
DU8341000
RTECS class
Drug; Reproductive Effector; Human Data
UN (DOT)
2811
Merck
12,4234
Beilstein/Gmelin
2054451
Beilstein Reference
6-06
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
Korea ECL
Listed

Properties.
Formula
C15H13FO2
Formula mass
244.27
Melting point, °C
113 - 114
Boiling point, °C
376
Vapor pressure, mmHg
3E-6 (25 C)
Density
1.279 g/cm3 (25 C)
Solubility in water
ll mg/L (25 C)
pKa/pKb
4.14 (pKa)
Heat of vaporization
65.8 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Hydrogen fluoride.

Fire.
Flash Point,°C
181
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Toxic. Toxic if swallowed. Possible sensitizer. Target organ(s): Kidneys.
   Ingestion
Toxic if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
II