Folpet

  • N-(Trichloromethylthio)phthalimide
  • 2-((Trichloromethyl)thio)-1H-isoindole-1,3(2H)-dione
Formula
C9H4Cl3NO2S
Structure
Description
White crystals.
Uses
Fungicide.

Registry Numbers and Inventories.
CAS
133-07-3
EC (EINECS/ELINCS)
205-088-6
EC Index Number
613-045-00-1
EC Class
Carcinogenic Category 3; Harmful; Irritant; Sensitising; Dangerous for the Environment
RTECS
TI5685000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector
Merck
12,4255
Beilstein/Gmelin
193373
Beilstein Reference
5-21-11-00118
EPA OPP
81601
Swiss Giftliste 1
G-1641
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C9H4Cl3NO2S
Formula mass
296.56
Melting point, °C
442 - 446
Vapor pressure, mmHg
<0.0001
Density
1.78 g/cm3 (25 C)
Solubility in water
Insoluble
Partition coefficient, pKow
2.85

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Goggles or a face shield.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Virtually non-volatile; stable when dry, but slowly hydrolyzes in water at ordinary temperature, rapidly @ high temperature or under alkaline conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
When heated to decomposition it emits very toxic fumes of hydrogen chloride, nitrogen oxides and sulfur oxides.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Carcinogin
CP65
Poison_Class
4
Exposure effects
The phthalimide fungicides contain the phthalimide moiety in common with phthalidomide, a known human teratogen. Captan has been teratogenic, fetotoxic, and/or embryotoxic in a variety of rodent species and caused stillbirths in dogs. Folpet was teratogenic in rabbits, chicks, and hamsters. Captafol has been embryo- or fetotoxic in experimental animals. <br>Captan, folpet, and captafol have all induced testicular degeneration in laboratory animals.
   Ingestion
Nausea, vomiting, and diarrhea may follow ingestion.
   Inhalation
Folpet is a respiratory tract irritant and can produce occupational asthma.
   Skin
Irritant and allergic contact dermatitis have been reported with captan, folpet, and captafol.
   Eyes
Folpet is an irritant of the eyes and mucous membranes.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.