Formamide

  • Methanamide
  • Carbamaldehyde
Formula
HCONH2
Structure
Description
Colorless, oily liquid.
Uses
Solvent; softener; intermediate in organic synthesis

Registry Numbers and Inventories.
CAS
75-12-7
EC (EINECS/ELINCS)
200-842-0
EC Index Number
616-052-00-8
EC Class
Toxic for reproduction Category 2
RTECS
LQ0525000
RTECS class
Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
Merck
13,4261
Beilstein/Gmelin
505995
Beilstein Reference
4-02-00-00045
Swiss Giftliste 1
G-1643
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
CH3NO
Formula mass
45.04
Melting point, °C
2
Boiling point, °C
210
Vapor pressure, mmHg
30 (129 C)
Vapor density (air=1)
1.6
Saturation Concentration
less than 0.22 mg/m3 at 20 C
Density
1.1334 g/cm3 (20 C)
Solubility in water
Miscible
Viscosity
3.23 cp (25 C)
Surface tension
58.9 g/s2 (20 C)
Refractive index
1.44911 (20 C)
Dipole moment
3.4 D (20 C)
Dielectric constant
109.5 (25 C)
Partition coefficient, pKow
-1.51
Heat of fusion
86.7 kJ/mol
Heat of vaporization
65/3 kJ/mol
Heat of combustion
-547 kJ/mol

Hazards and Protection.
Storage
Do not store in direct sunlight. Keep refrigerated. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizing agents, acids, bases, aluminum.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia and/or derivatives.

Fire.
Flash Point,°C
175
Autoignition, °C
500
Upper exp. limit, %
19.0
Lower exp. limit, %
2.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Cool containers with flooding quantities of water until well after fire is out.
Hazards
Toxic fumes emitted on decomposition (carbon monoxide and ammonia), beginning at 180 - 210C. Behavior in Fire: Vapor will burn in air above 310F.
Combustion products
Toxic fumes emitted on decomposition (carbon monoxide and ammonia), beginning at 180 - 210C.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 10 ppm; 18 mg/m3 (skin) (ACGIH 1996). NIOSH REL: TWA 10 ppm (15 mg/m3) skin
Poison_Class
3
Exposure effects
Prolonged or repeated exposure may cause adverse reproductive effects. May cause fetal effects.
   Ingestion
May cause irritation of the digestive tract.
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
USCG CHRIS Code
FAM
 
HS Code
2924 19 00
 
IMO Chemical Code
18
IMO Pollution Category
D