Formestane

  • CGP-32349
  • 4-Hydroxy-4-androstene-3,17-dione
  • 4-Hydroxy-delta(sub 4)-androstenedione
Formula
C19H26O3
Structure
Description
White powder.

Registry Numbers and Inventories.
CAS
566-48-3
R: 20/21/22
S: 36/37
RTECS
BV8152500
Merck
12,4267
Beilstein/Gmelin
1889793

Properties.
Formula
C19H26O3
Formula mass
302.41
Melting point, °C
199 - 202
Vapor pressure, mmHg
4.9E-11 (25 C)
Density
1.19 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
9.31 (pKa)
Partition coefficient, pKow
2.66

Hazards and Protection.
Storage
Store cool, dark and dry.
Protection
Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.
Small spills/leaks
Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.

Fire.
Fire fighting
Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.
Combustion products
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful by inhalation, in contact with skin and if swallowed.

First aid
 
   Ingestion
If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.
   Inhalation
Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.
   Skin
Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.
   Eyes
Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.

Transport.