Formononetin

  • Formononetol
  • Biochanin
  • Daidzein 4'-methyl ether
  • 7-Hydroxy-4'-methoxyisoflavone
  • 7-Hydroxy-3-(4-methoxyphenyl)-4-benzopyrone
  • 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)
Formula
C16H12O4
Structure
Description
Solid.
Uses
Treatment and prevention of osteoporosis.

Registry Numbers and Inventories.
CAS
485-72-3
EC (EINECS/ELINCS)
207-623-9
Merck
12,4271
Beilstein/Gmelin
237979
Beilstein Reference
5-18-04-00089

Properties.
Formula
C16H12O4
Formula mass
268.26
Melting point, °C
290 - 293
Solubility in water
Insoluble
pKa/pKb
7.54 (pKa)

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
No data.
Incompatibilities
Strong oxidizing agents, acids, acid chlorides, carbon dioxide, acid anhydrides.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
   Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed.
   Inhalation
Causes respiratory tract irritation. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. May be harmful if inhaled. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
   Skin
Causes skin irritation. May be harmful if absorbed through the skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.