Formothion

  • G-38
  • Phosphorodithioate
  • Aflix
  • Afliz (Sandoz)
  • Anthio
  • Anthio 25
Formula
C6H12NO4PS2
Structure
Description
Viscous yellow oil or a crystalline mass.
Uses
It is a contact and systemic insecticide and acaricide against a wide range of sucking and mining insects such as chewing insects (cydia pominella and epilachna beetles) and spider mites.

Registry Numbers and Inventories.
CAS
2540-82-1
EC (EINECS/ELINCS)
219-818-6
EC Index Number
015-057-00-7
EC Class
Harmful
RTECS
TE1050000
RTECS class
Agricultural Chemical and Pesticide; Mutagen
Merck
12,4273
Beilstein/Gmelin
5942199
EPA OPP
366400
Swiss Giftliste 1
G-1644
Austrailia AICS
Listed
Korea ECL
Listed

Properties.
Formula
C6H12NO4PS2
Formula mass
257.27
Melting point, °C
25.0
Vapor pressure, mmHg
0.0000085
Density
1.361 g/cm3 (20 C)
Solubility in water
water

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
This compound is an organophosphorus insecticide. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Small dry spills: with clean shovel, place material into clean, dry containers and cover; move containers from spill area. Large spills: dike far ahead of spill for later disposal.
Stability
Hydrolyzed by water to dimethoate and (dimethoxyphosphinothioylthio)acetic acid; dt50 < or = 1 day @ pH 3-9 and 23 C. Hydrolyzed more rapidly in alkaline media. Dilute solutions in non-polar organic solvents are

Fire.
Fire fighting
This compound is an organophosphorus insecticide. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site.This compound is an organophosphorus insecticide. Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam. Move container from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter material.
Hazards
When heated to decomposition, it emits very toxic fumes of nitrogen oxides, phosphorus oxides and sulfur oxides. This compound is an organophosphorus insecticide. Some of these materials may burn but none of them ignite readily. Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Avoid alkaline pesticides; hydrolyzed by water especially under alkaline conditions.

Health.
Poison_Class
3
Exposure effects
Reduced body temperature or elevated body temperature may occur. Early giddiness, anxiety headache, and restlessness followed by ataxia, drowsiness, and confusion are common with moderate to severe exposures. Fasciculations, profound weakness, coma and seizures may develop in severe cases. CNS depression and seizures may be more common in children than adults.
   Ingestion
Nausea, vomiting, abdominal cramps, and diarrhea are common muscarinic effects.
   Inhalation
Formothion is one of the least toxic systemic organophosphates. Formothion is a compound of low to moderate toxicity. It causes the depression of cholinesterase, leading to accumulation of acetylcholine in the nervous system, which is believed to be responsible for the symptoms.
   Skin
Summary
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur. Salivation commonly occurs.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
USCG CHRIS Code
FRM