Gabapentin

  • Neurontin
  • 1-(Aminomethyl)cyclohexaneacetic acid
Formula
C9H17NO2
Structure
Description
Off-white powder.
Uses
Anticonvulsant with unknown mechanism of action. Exhibits antinociceptive, anxiolytic, neuroprotective and anti-epileptic effects.

Registry Numbers and Inventories.
CAS
60142-96-3
EC (EINECS/ELINCS)
262-076-3
61 36/37/38
53 22 26 36/37/39 45
RTECS
GU6496000
RTECS class
Drug
Merck
12,4343
Beilstein/Gmelin
2359739
Beilstein Reference
6-14
New Zealand
Listed

Properties.
Formula
C9H17NO2
Formula mass
171.24
Melting point, °C
165 - 152
Boiling point, °C
314
Vapor pressure, mmHg
0.0001 (25 C)
Density
1.257 g/cm3
Solubility in water
Very soluble
pKa/pKb
4.72 (pKa)
Heat of vaporization
61.1 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves. Wear disposable coveralls and discard them after use.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
144
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
4
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Toxic. May cause harm to the unborn child. Irritating to eyes, respiratory system and skin. Target organ(s): Nerves. Pancreas.
   Skin
Causes skin irritation. Multiple Routes: May be harmful by inhalation, ingestion, or skin absorption. Vapor or mist is irritating to the eyes, mucous

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.