Gallodesoxycholic acid

  • Chenodesoxycholic acid
  • Anthropodesoxycholic acid
  • 7a-Hydroxylithocholic acid
  • 3a,7a-Dihydroxy-5b-cholanoic acid
  • 17b-(1-Methyl-3-carboxypropyl)etiocholane-3a,7a-diol
  • Cholan-24-oic acid, 3,7-dihydroxy-, (3a,5b,7a)-
Formula
C24H40O4
Structure
Description
White solid.
Uses
Bile acid. A detrrgent used to solubilize fats. Used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.

Registry Numbers and Inventories.
CAS
474-25-9
EC (EINECS/ELINCS)
207-481-8
RTECS
FZ1980000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
Merck
12,2096
Beilstein/Gmelin
3219887
Beilstein Reference
4-10-00-01604
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C24H40O4
Formula mass
392.57
Melting point, °C
164.85 - 165.85
Density
1.162 g/cm3
Solubility in water
Insoluble
pKa/pKb
4.76 (pKa)

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
Chronic ingestion may cause liver damage. Prolonged or repeated exposure may cause adverse reproductive effects.
   Ingestion
The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.