Glafenine

  • Glycerylaminophenaquine
  • 1-Glyceryl N-(7-chloro-4-quinolyl)anthranilate
  • 2,3-Dihydroxypropyl-N-(7-chloro-4-quinolinyl)anthranilate
  • 4-[(2-Carboxyphenyl)amino]-7-chloroquinoline a-monoglyceride
Formula
C19H17ClN2O4
Structure
Uses
Analgesic.

Registry Numbers and Inventories.
CAS
3820-67-5
EC (EINECS/ELINCS)
223-315-7
RTECS
CB2687000
RTECS class
Drug; Human Data
Merck
12,4443
Beilstein/Gmelin
497124
Beilstein Reference
6-22
Japan ENCS (MITI)
Listed

Properties.
Formula
C19H17ClN2O4
Formula mass
372.81
Melting point, °C
171
Boiling point, °C
618
Vapor pressure, mmHg
4E-16 (26 C)
Solubility in water
Insoluble
pKa/pKb
6.49 (pKb)
Heat of vaporization
96.3 kJ/mol

Hazards and Protection.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
328
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful. Harmful if swallowed.
   Ingestion
Harmful if swallowed.
   Inhalation
May be harmful if inhaled.
   Skin
May be harmful if absorbed through the skin.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.