Gliclazide

  • N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea
  • 1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea
Formula
C15H21N3O3S
Structure
Uses
Medicine used to help control blood sugar levels in people with type 2 diabetes

Registry Numbers and Inventories.
CAS
21187-98-4
EC (EINECS/ELINCS)
244-260-5
RTECS
YT4500000
RTECS class
Drug; Reproductive Effector; Human Data
Merck
12,4448
Beilstein/Gmelin
1657836
Beilstein Reference
6-20
Korea ECL
Listed

Properties.
Formula
C15H21N3O3S
Formula mass
323.42
Melting point, °C
180 - 182
Density
1.319 g/cm3
Solubility in water
Slightly soluble
pKa/pKb
7.82 (pKb)

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Protective gloves. Chemical safety goggles.
Respirators
Wear dust mask.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures. Heat.
Incompatibilities
Acids, Bases, Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

Fire.
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
0
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May be harmful if swallowed.
   Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.