Glutaraldehyde

  • 1,5-Pentanedial
  • Glutaric dialdehyde
  • Glutaral
  • 1,3-Diformylpropane
Formula
C5H8O2
Structure
Description
Colorless to yellowish liquid with a pungent fruity/medicinal odor. A 5-25% aqueous solution. Physical properties are based on a 25% solution.
Uses
Microbiocide, Fungicide

Registry Numbers and Inventories.
CAS
111-30-8
EC (EINECS/ELINCS)
203-856-5
EC Index Number
605-022-00-X
EC Class
Toxic; Corrosive; Sensitising; Dangerous for the Environment
R 23/25 34 42/43 50
S 26 36/37/39 45 61
RTECS
MA2450000
RTECS class
Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
2810
Merck
13,4485
Beilstein/Gmelin
605390
Beilstein Reference
4-01-00-03659
EPA OPP
43901
Swiss Giftliste 1
G-42675
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C5H8O2
Formula mass
100.12
Melting point, °C
-10
Boiling point, °C
101
Vapor pressure, mmHg
0.6 (25 C)
Vapor density (air=1)
0.8
Evaporization number
0.9 (butyl acetate=1)
Critical temperature
360
Critical pressure
41.1
Density
1.014 g/cm3 (20 C)
Solubility in water
Miscible
Surface tension
<80 g/s2
Refractive index
1.43 (20 C)
Partition coefficient, pKow
-0.34
Heat of vaporization
42.5 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
D1B D2B E
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Stable under ordinary conditions of use and storage. May discolor on exposure to air. Polymerization may occur at high temperatures or in alkaline solutions (above pH 9), but it is not hazardous.
Incompatibilities
Avoid contact with strong oxidizers, strong bases.
Decomposition
When heated to decomposition it emits acrid smoke and fumes.

Fire.
Flash Point,°C
66
Fire fighting
Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Use any means suitable for extinguishing surrounding fire.
Fire potential
This material will not burn until the water has evaporated. Residue can burn.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 0.2 ppm; 0.82 mg/m3 (ceiling values) (ACGIH 1992-1993). NIOSH REL: C 0.2 ppm (0.8 mg/m3) See Appendix C (Aldehydes)
Poison_Class
3
Exposure effects
Seizures and CNS depression were noted in animals given intravenous glutaraldehyde.
   Ingestion
Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea. May cause chemical burns of the mouth, throat, esophagus and stomach with discomfort or pain in the chest and abdomen. Aspiration into the lungs may occur during swallowing or vomiting, resulting in lung damage.
   Inhalation
Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath. Heating the solution may result in more severe irritant effects.
   Skin
Causes irritation to skin. Symptoms include redness, itching, and pain. Prolonged contact may cause skin burns. May be absorbed through the skin with possible systemic effects.
   Eyes
Corrosive! Vapors are irritating and may cause damage to the eyes. Contact may cause severe burns and permanent eye damage.

First aid
 
   Ingestion
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
2810
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
GTA
 
IMO Chemical Code
17
IMO Pollution Category
D
IMO Hazard code
S